Single IRB of Record requirements when the University of Iowa IRB is serving in a lead IRB role
Federal agencies require the use of a single IRB (sIRB) for federally funded research conducted at multiple sites. This means one IRB oversees research conducted at some or all of the study sites. The budget must include the fees for this type of IRB review and this type of research may require some additional approvals and agreements. Researchers can access information about UI IRB fees for budget planning.
If you are planning to submit a grant proposal to the National Institutes of Health (NIH) or any other federal agency that requires the sIRB model, complete the Pre-Grant Submission Survey as soon as you become aware of the award notice. Plan ahead and complete this survey well in advance, especially if the Iowa IRB is either serving as a lead IRB as an expectation of the grant!
If you have questions or need any assistance, contact the External IRB Team at uirb-external@uiowa.edu.
Recent changes in federal policy and regulatory requirements are driving the need to develop systems to support a new single IRB (sIRB) review model for multi-site research.
The University of Iowa and Washington University in St. Louis were awarded a grant from the NIH to co-develop myProject, an IT system solution for institutions to effectively implement and manage their roles as relying institutions and reviewing IRBs under different single IRB (sIRB) models in multi-site research. myProject will not only meet the needs of a relying institution or reviewing sIRB, but also provide simple tools to reduce burden and support compliance for researchers tasked with working with a variety of sIRBs and their varied operating procedures and reporting requirements.
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Help the Institute for Clinical and Translational Science at the University of Iowa continue making new strides in medical research by citing the NIH CTSA program grant UM1TR004403.