The Healthcare Worker Exposure Response & Outcomes (HERO) Registry invites US healthcare workers to share clinical and life experiences in order to understand the perspectives and problems faced by those on the COVID-19 pandemic front lines. The registry will unite America’s healthcare workers into a community to facilitate rapid-cycle research, including an upcoming large study of hydroxychloroquine’s effectiveness in preventing coronavirus infections in healthcare workers. The HERO research program leverages PCORnet®, the National Patient-Centered Clinical Research Network, and is funded by the Patient-Centered Outcomes Research Institute (PCORI). To learn more, please visit: https://heroesresearch.org